O.S.I.

The Office of Secret Intelligence, or O.S.I., is a highly secretive, elite agency of the United States government. They have been protecting America since the Second American Revolution (the invisible one) through espionage, assassination, and any other means necessary.

Duties and operation
OSI's duties include protecting America from any threats, from within or out, by any means necessary. To that end they have the ability to issue a License to Kill to their agents. Notably, many of their high ranking agents have a prominent single characteristic, reflected in their clothing ever since they relaxed the dress code. Lower ranked agents wear uniforms.Their current headquarters are a massive, flying aircraft-carrier.

Recently, their most important duty appears to be regulating the American hero, or protagonist, community. It's O.S.I. that sets the rules, assigns the bodyguards, and offers aide to counteract the villainous Guild of Calamitous Intent. They also have the ability to gather various experts, from O.S.I., The Guild, and other organizations, when necessary to fight against a mutual threat.

From the beginning of the series, O.S.I. was led by the eccentric General Timothy Treister. Glimpses into their history have revealed that Colonel Hunter Gathers was at one time a one-on-one training agent. Before the reemergence of The Guild of Calamitous Intent, they mostly fought S.P.H.I.N.X., often in large battles. As of the end of season 4, General Treister trusts the charge of OSI to former member (and current S.P.H.I.N.X. leader) Hunter Gathers when Treister decides to search off planet for the cure to his "peepee cancer".