Agent Honeydew is an operative of Global Security as well as the faithful ally of Dexter's secretly super-heroic laboratory specimen, Monkey. Honeydew has a telepathic link with the simian superhero, and can summon him when events threaten the world with chaos. Besides her connection to Monkey, Agent Honeydew is herself a valued operative of Global Security, a skilled fighter who knows how to handle weapons. She and Monkey seem to be good friends, perhaps even romantic partners though it has since become non-canon as evidenced in "A Quackor Cartoon", with Monkey discovering that Quackor is female and becomes enamored with her, ending their rivalry altogether.
During her training, Agent Honeydew is a skilled fighter who is proficient in firearms. She also has the ability to somehow contact Monkey when he is needed.