|“||Not fire, nor water, nor wind can destroy the World of Truth, Guaypar. Nor any fury.||„|
|~ Anamaya admonishing Guaypar of underrating a deceased oracle's warning of Atahualpa's downfall|
After Anamaya's been captured by Inca raiders who kill her mother, she gains the attention of Huyana Capac himself. The dying Inca ruler believes that the girl with eyes as blue as the waters of the sacred Lake Titicaca has been sent to ensure his passage to the Other World by Quilla the Moon Goddess and ignores his advisers' requests to sacrifice her. In his deathbed, Huyana Capac confides to Anamaya secrets regarding the past and the future of the Inca Empire, but afterwards the girl can't remember the specifics.
Anamaya is appointed as Coya Camaquen, the wife and guardian of Huyana Capac's golden statue called the Sacred Double. The position makes her one of the most revered leads among Incas. She's then involved in the Inca Civil War and Francisco Pizarro's conquest, guided by Huyana Capac's last words she remembers by flashes and as visions. She first supports Atahualpa and later Manco Inca Yupanqui as their confidants.
Right before the Battle of Cajamarca, Anamaya meets and falls in love with a conquistador named Gabriel Montecular y Flores who has a birthmark shaped like a puma. One of Huyana Capac's last words ("trust the puma") ties Anamaya to Gabriel throughout the war between Incas and Spaniards as they have to witness the darker aspects of human nature and deal with their conflicting loyalties and Huyana Capac's predictions coming true.