Annie Knitts is a female fourth grader from South Park. She was originally voiced by Mary Kay Bergman in "Tweek vs. Craig", however, Mona Marshall later took over that role.
She wears a brown collarless jacket and black pants. Her hair is short, light blonde and tight-curly. In "Stupid Spoiled Whore Video Playset", she wore an aquamarine tube top, a teal-and-aquamarine wrap skirt, and white shoes.
She wears a pink pajama shirt with a light purple collar when she goes to bed, as shown in "Skank Hunt".
Annie is portrayed as a kind person; however, this leads to her being a target for bullying. In South Park: The Stick of Truth, she is seen upset over three older girls taking her Justin Bieber doll.
Annie is also a rather naive person, admitting that she didn't know what a queef was in "Eat, Pray, Queef". Despite her shortcomings, she showed a trait of leadership and convinced Wendy and her friends to break up with their boyfriends in "Skank Hunt" in an attempt to get back at them for Skankhunt42's misdeeds.