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Pinky, are you pondering what I'm pondering?
~ Brain
The same thing we do every night, Pinky. Try to take over the world!
~ Brain

The Brain is the main antagonist of Animaniacs, one of the titular protagonists of Pinky and the Brain and of Pinky, Elmyra & the Brain, and a cameo character in Freakazoid!. He has an oversized brain, and is very knowledgeable. However, his attempts to conquer the world always fail. But the Brain doesn't let that bring him down, and by next night he will have a new trick up his sleeve.

He is voiced by Maurice LaMarche, who also voices Vincent Van Ghoul, Chancellor Neighsay, Inspector Gadget and Mr. Big.


Brain is a genius with a relaxed and cocksure personality. He almost never loses patience, even when Pinky commits silly errors that mess his plots completely (though he displays clear aggravation frequently). What's more, he seems to be self-centered.

Despite his plots, he truly believes that he will make the world a better place, will never resort to killing to accomplish his goals and deep down he cares deeply about Pinky. There are also some world domination plans even he will not attempt as they're sick even to him: for instance, he was unwilling to use a plan involving selling cigarettes to kids.

Brain's good intentions are highlighted with his rival called Snowball, a hamster who planned to conquer the world as well, but he's far more heinous and callous. Brain is grossed-out by Snowball's methods and will stop at nothing to prevent him from taking over the world.


Both Brain and Pinky are laboratory mice who underwent an experiment to make them rational. The experiment had different results on each of them, turning Brain into a super genius, while Pinky also becomes sentient but incredibly stupid. Brain then decided he would use his superior knowledge to take over the world and make it a better place using his intellect. He convinced Pinky to aid him in his plans, and the two of them try a new plan to achieve world domination every night.

Heroic Acts

  • He occasionally foils Snowball's evil plans.
  • He saved his sidekick, Pinky from getting killed by drowning in quicksand.
  • He sometimes plans to save the world.
  • Despite his seemingly evil personality, it turns out that he makes it his goal to make the world a place of kindness, equality and happiness for all.
  • He truly believes that the world would be a better, happier place if he was in charge; as it is justified by portraying real world's leaders as either egotistic, incompetent or plain crazy (or all at once).
  • He tried to save Snowball from drowning in a waterfall.
  • He, along with Pinky, tried to save Billie from being kidnapped.


See Also