Curtis Connors is a supporting character in The Amazing Spider-Man and is a mentor to Spider man. However he gets an acident which turns him into the Lizard and the main villain of them film. He wanted to use his reserch to help human life.
Dr. Connors is first seen attemting to engineer a revolutionary regeneration serum to help re-grow limbs and human tissue. He worked with Richard Parker on the cross-species genetics theory, but when Richard disappeared, all seemed lost until Connors met Peter Parker, Richard's son.
Their first meeting occured when Peter and his friends are having tour in OsCorp tower, where Peter learned that Connors is used to be a friend of his father. Later, Peter visited him again, where Connor thought that he came for autograph. Instead, Peter introduces himself as Richard Parker's son and gives Connors his father's "decay rate algorithm", the missing piece in Connors' experiments on regenerating limbs, which is especially important to Connors since he is missing his right arm.
Afterwards, with Peter's help, he managed to complete the formula and tries it on the guinea pigs, two white mouses named Fred and Wilma.