Giuseppe was born in Italy and was regarded as Italy's best forger and safe cracker. He fled to Empire Bay, U.S.A when Benito Mussolini took control of Italy. In Empire Bay he had no family and only lived for his craft, serving as an arms dealer, master safecraker and seller of thieving tools, such as lock picks.
Joe Barbaro already knew Giuseppe for a long time, saying that his shop was a "haven for thieves". Barbaro introduced his friend Vito Scaletta to Giuseppe, and Giuseppe helped Vito in learning how to pick a lock. Giuseppe' Shop is available during the entire game, where Vito can buy a special pistol, a magnum revolver, molotov cocktails, lock picks and fake documents. Later in the game, Vito goes to Giuseppe's and asks him if he saw Joe lately. Giuseppe says that Joe was recently there, but Frank Vinci's mobsters arrived and said "Mr. Vinci wants a word with Joe" and then took him.
- Home Sweet Home.
- Stairway to Heaven.
- Giuseppe is similar to Salvatore from Mafia: The City of Lost Heaven.