They originally met at Meizuru university for Lucien genetic upgrades around A.D. 2134, although it is not necessarily canon, they were both misfits within their year, and so became friends. Around A.D. 2137, just before graduation from Meizuru university, they played a prank on their friends, convincing them that they were both psychic. Shortly afterwards, news reached the 3WA and they were scouted for recruitment and tested by a parapsychology institute. The pair cheated every which way possible (the really short skirts were Kei's idea), and they tested positive for clairvoyance, the 3WA considered this to be useful and hired them.
Although outwardly they almost constantly fight and bicker with each other, they are both loyal best friends, always pairing up together to deck anyone that calls them by their "Dirty Pair" nickname. The two girls are named Kei and Yuri. The Lovely Angels also own a alien cat named Mughi.