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Madame Web (Cassandra Webb) is a fictional character appearing in American comic books published by Marvel Comics. Madame Web first appeared in The Amazing Spider-Man #210, published November 1980, and was created by the late writer Denny O'Neil and artist John Romita, Jr. She is usually depicted as a supporting character in the Spider-Man comic book series. She is depicted as an elder woman with myasthenia gravis and thus was connected to a life support system that looked like a spider web. Due to her age and medical condition Madame Web never actively fought any villains.


Madame Web was a clairvoyant, and precognitive mutant who first showed up to help Spider-Man find a kidnap victim. Madame Web was not one of the mutants that lost their power during the Decimation storyline. She was attacked by Sarah and Ana Kravinoff, who killed her, but not before she was able to pass her powers of precognition as well as her blindness on to Julia Carpenter, who became the next Madame Web. Webb is the grandmother of the fourth Spider-Woman, Charlotte Witter.


Born in Salem, Oregon, Cassandra Webb is a paraplegic and is blind after being struck with myasthenia gravis, a disease that erodes the nervous system. She was connected to a life support system made by her husband. She knows Spider-Man's secret identity and helps him occasionally. She is the grandmother of the fourth Spider-Woman, Charlotte Witter.

Powers and abilities

Madame Web is a mutant that possesses psychic sensory powers including telepathy, clairvoyance, prescience, and the ability to sense the presence of psionic powers in others. She can also perform psychic surgery and appear to others in spirit (astral) form. She has a gifted intellect.

When dying she displayed the ability to transfer her mutation to another individual, Julia Carpenter, as well as her blindness.

Madame Web was a victim of myasthenia gravis, a disorder of neuromuscular junction transmission. As a result, she was an invalid entirely dependent on external life support for survival. This is no longer the case as she was cured of the condition some time ago. She is also blind. Madame Web is cybernetically linked to a spider-web-like life support chair which attends to all of her bodily needs.

Other versions

  • A version of Madame Web makes a brief appearance in the heroic fantasy world of Avataars: Covenant of the Shield as "the Widow of the Web", a spider-goddess who grants Webswinger (the Spider-Man parallel) his powers.
  • Webb also appeared during the "House of M" storyline as a therapist employed by S.H.I.E.L.D.
  • Madame Web died in the MC2 universe, but her reputation has inspired an entire temple of prophetic acolytes.
  • Madame Web appeared in Ultimate Spider-Man. In issue #102, she is part of the psych team that plans to change Ultimate Spider-Woman's memories. She appears in a wheelchair (implying paralysis) and blind, similar to the classic version. However, she is younger than that version of the character.