Miss Kitty is the love interest of Tiger from the movie, An American Tail: Fievel Goes West.
She is voiced by Amy Irving.
She was first seen as Tiger's girlfriend who's leaves him to find a new life out West, tired of the life of an alley cat and remarking that perhaps she's looking for a cat that is "more like a dog."
She wasn't seen again until Miss Kitty who's now a diva and reveals that she came out west at the request of Cat R. Waul, an action she now seems to regret.
Cat R. Waul tells Miss Kitty to put Tanya on stage. With a little encouragement from Miss Kitty, Tanya performs to positive feedback.
At Green River, a giant mousetrap has been disguised as bleachers for a ceremony honoring the opening of Cat R. Waul's saloon. But before the trap can be tripped, the three foil the plot using their wits and their slingshots to combat Cat R. Waul's feline henchmen.
Tanya and Ms. Kitty soon learn of Cat R. Waul's true intentions and gets the rest of the mice to get off the trap.
But towards the end of the fight, Chula captures Ms. Kitty as hostage, threatening to drop her from the tower.
Then, Tiger was enraged and overcomes his Arachnophobia he had earlier by unleashing his "inner dog" to save Ms. Kitty and using a pitchfork and Chula's web as a lasso with the spider trapped on it and then hurtles Cat R. Waul and his gang out of town by using the mouse trap.
The cats fly into the air, then land into a mailbag. A passing train picks up the bag and leaves, and Cat R. Waul gets reluctantly adopted by a cat-obsessed female passenger, just as he is about to plot revenge.
Enchanted by his new personality, Miss Kitty and Tiger are reunited and kiss.