Misty is the tritagonist of the original Pokémon anime series. Although Misty is the leader of the Cerulean Gym in the games, she left the Gym to her three older sisters prior to traveling with Ash in the anime. She was Ash's first female traveling companion.
She is voiced by Mayumi Iizuka and Ayane Sakura in the Japanese version, Rachael Lillis in the 4Kids English version and Michele Knotz in the TPCi English version.
In both the Original Series and the Sun & Moon Series, Misty is shown wearing a yellow crop top and turquoise denim jean shorts held up with red suspenders. She also wore red, yellow and white sneakers.
In the Advanced Generation series, Misty is shown wearing a yellow sleeveless top or vest with a large blue button on the front and matching shorts, worn over some sort of dark-red under-all.
In the anime
In the anime, Misty lives in Cerulean City and has three sisters named Daisy, Violet and Lily. She first came across Ash when she accidentally fished him and his Pikachu out of a river while fishing for water Pokémon. Soon after this incident, Ash borrowed her bike, attempting to flee from a flock of wild Spearow. The bike was later charred by a Thundershock from Pikachu. Misty told Ash she would not leave him alone until he replaced the bike and committed to following him on his journey, and the two soon became close friends. After retrieving her bike at the end of the Johto League Silver Conference, she returns to the Cerulean Gym and resumes her duties as the Gym Leader.
As such, she was not featured as a character in the later seasons until she appeared again in the Sun & Moon series, only appearing in a few episodes and specials before that. She became a central character in Pokemon Chronicles, a spin-off to the Pokémon anime. She maintains her friendship with Ash and once greeted him when he returned to Pallet following a long stint in Hoenn. In the early episodes, Misty is depicted as having a wicked temper, stubborn temperament, and little patience. As the series progresses, however, she gradually shows herself to be kind and sensible.
Although she regularly displays a somewhat romantic streak, Misty constantly reins in Brock when he becomes enamored with cute girls (style of Barbie dolls), often pulling him away by the ear. She has a slight rivalry with Ash, and she is also terrified of most Bug-type Pokemon. Misty aims to be a world-class Water-type Pokemon trainer despite her sisters' ridicule.
In the games
Like in the anime, Misty lives in Cerulean City, and she is the gym leader of this city. In all Kanto and \ or Johto Games (Red, Blue \ Green, Japanese Blue, Yellow, Gold, Silver, Crystal, FireRed, LeafGreen, HeartGold and SoulSilver), she gives the Cascade Badge to any trainer who defeats her (such as Red, Blue, Leaf, Ethan, Kris or Lyra).
- In the anime, Misty resembles Iris in the Best Wishes Series, as they both argued with Ash, and their game counterparts are gym leaders.
- However, Misty returned in the Advanced Generations Series, and in the Sun & Moon Series, along with Brock while Iris did not appear after she left Ash in the end of the Best Wishes Series.
- Also, unlike Misty, who is the gym leader of Ceeulean City in all Kanto and Johto games, Iris is the gym leader of Opelucid City only in Pokémon White.
- Psyduck, One of her earliest water type catches in the whole of the anime, also happens to share a 320 base stat total with Iris' signature Pokémon, Axew.
- Former director and storyboard artist of the Pokémon anime, Masamitsu Hidaka, stated in an interview that Misty will not return as a main character in future seasons, but will continue to make guest appearances from time to time.
- Misty is similar to Cera from The Land Before Time as both Cera and Misty can lose their temper sometimes. Also, Cera has orange skin while Misty has orange/red hair. 
Gym Leaders, Trial Captains, and Island Kahunas
Elite Four, Finalists, and Quarter Finalists
Groups and Organizations