She is the wife of Grandpa Smurf, the mother of Papa Smurf, the grandmother of the Smurfs, as well as the adoptive grandmother of Smurfette and the Smurflings.
She is also the mistress of Smoogle who was an marsupial pet animal.
She is voiced by Susan Blu.
Nanny Smurf is an older Smurfette who was imprisoned in the haunted house called Castle Captor.
But she was rescued by her pet Smoogle on the Smurfs' orders.
Nanny Smurf starts to befriend Smurfette after she and Smurfette became friends after taking the responsability.
She is better known to wear glasses just like Brainy Smurf and Grandpa Smurf before her. She loves to meet Don Smurfo.
She is the elder female Smurf who forms the friendship and relationship with her husband Grandpa Smurf.
Like Grandpa, she likes to tell the Smurfs the stories by stopping the antagonists like Gargamel and his mischevious pet cat Azrael.