She is voiced by Saori Hayami in the Japanese and Brina Palencia in the English.
She have rare red hair and green color for her eyes.
Shirayuki is a bright and resourceful girl, determined, able to speak her mind, and knowledgeable in both botany and medicine. Whenever there is a problem or conflict, she often takes matters into her own hands. She later learns to rely on others, especially Zen.
She was born with rare red hair, she often has to hide it due to how it easily attracts attention. She escapes from the kingdom of Tanbarun after its prince orders her to become his concubine. Independent and persistent, she meets Zen on her second day in the kingdom of Clarines and befriends him after tending to his wounds. Later, she is accepted as a royal pharmacist and trains under Garack and Ryu. Shirayuki has demonstrated her abilities as a pharmacist in various situations, particularly in identifying and controlling disease outbreaks in foreign areas. She has a close relationship with Zen, and falls in love with him over the course of the story despite opposition due to their difference in social status. She moves into the east wing of Wistal Castle in chapter 49, and is later reassigned as a pharmacist to Lyrias for two years in chapter 53.
- "I never learned how ride a horse!"
- "Look! There's Lord Haruka!...Come on, why aren't you looking...?"
- She and Chise Hatori have something in common:
- They have red hair and green eyes.
- Her English Voice Actress, Brina Palencia is best known for voicing as Ciel Phantomhive from Black Butler series, Eve, Tearju Lunatique from Black Cat, Tamama from Sgt. Frog, Holo from Spice & Wolf series, Ennis Prochainezo from Baccano!, Miharu Rokujo from Nabari no Ou, Rei Ayanami from Rebuild of Evangelion, Ryōko Ōkami from Ōkami-san and her Seven Companions, Kazumi Yoshida from Shakugan no Shana series, Yumi Azusa from Soul Eater, Ibuki Mioda from Danganronpa 3: The End of Hope's Peak High School series, Isuzu Sohma from Fruits Basket, Natsuki Shinohara from Summer Wars, Touka Kirishima from Tokyo Ghoul series, Kurumu Kurono from Rosario + Vampire, Tony Tony Chopper from One Piece series, Puar, Chaozu from Dragon Ball Kai, Hideyoshi Kinoshita, Yuuko Kinoshita from Baka and Test - Summon the Beasts and Moro from xxxHolic.