He is voiced by Crispin Freeman.
Winston was initially a subject in the tests on genetically enhanced gorillas that took place in Lucheng Interstellar's Horizon Lunar Colony. He had shown unusually rapid development, so Dr. Harold Winston, from whom Winston got his name, took personal care of him. Through him, Winston learned science and helped in the doctor's research. The doctor also gave Winston his signature glasses. When the other gorillas started to revolt against the colony, Winston escaped to Earth.
Winston found a new home as a member of Overwatch. There, he became both a soldier and a scientist. His skill in combat led to him defeating Doomfist, and his craftsmanship helped him save the life of Tracer by building her chronal accelerator.
After the collapse of Overwatch, Winston and Athena retreated to Watchpoint: Gibraltar, from which he launched a satellite drone in the event that Overwatch would need to be recalled. He included with it a personal message to the former agents.
In Recall, Winston's lab at the Watchpoint was invaded by Reaper and several Talon agents. He was able to dispatch them, and afterwards decided to finally recall Overwatch agents to active duty.
In the Cinematic Trailer, Winston worked with Tracer to stop Widowmaker and Reaper from stealing Doomfist's gauntlet. Though the gauntlet was damaged, there were no casualties.
Winston is an awkward yet gentle giant, never wanting to inflict unnecessary harm on innocents and often stuttering whenever someone compliments him. He is a huge fan of Overwatch and really cares about its members to the point of calling them family in the Are You With Us? cinematic teaser. He also seems to have a love for peanut butter and bananas, as shown in the Recall animated short, his Voice Lines and Emotes.
Winston is rather smart when it comes to craftsmanship, as proven by his ability to create the chronal accelerator. He is even considered an intelligent scientist as well, and he hates being called a monkey.